Global Metal

7 Countries, 3 Continents, 1 Tribe - die Ausgangshypothese des Films wird im Untertitel beschrieben. Dieser soll den fortschreitenden Globalisierungsprozess von Heavy Metal dokumentieren und dabei vor allem die Zusammengehörigkeit und die Ähnlichkeiten von allen metalheads weltweit dokumentieren. Diese These wirft allerdings die Frage auf, ob ein bestimmter Musikstil es schaffen kann, trotz aller rund um den Globus vorhandenen Kulturdifferenzen und der daraus resultierenden Probleme Menschen zu begeistern und einen prägenden Einfluss auf ihr Leben auszuüben, eine Frage, der mit einem wissenschaftlich anthropologischen Forschungsansatz auf den Grund zu gehen sich lohnen könnte. Dunn propagiert es zu Beginn des Films, daran an die fast soziologische Perspektive seines ersten Films METAL: A HEADBANGER‘S JOURNEY (Kanada 2005) anknüpfend

The Infinite Index: Information Retrieval on Generative Text-To-Image Models

Conditional generative models such as DALL-E and Stable Diffusion generate images based on a user-defined text, the prompt. Finding and refining prompts that produce a desired image has become the art of prompt engineering. Generative models do not provide a built-in retrieval model for a user's information need expressed through prompts. In light of an extensive literature review, we reframe prompt engineering for generative models as interactive text-based retrieval on a novel kind of "infinite index". We apply these insights for the first time in a case study on image generation for game design with an expert. Finally, we envision how active learning may help to guide the retrieval of generated images.Comment: Final version for CHIIR 202

Если человечество не изменит концепцию своего развития, оно погибнет

Сложная современная политическая, социально-экономическая, межнациональная, религиозная и пр. ситуация в мире требует от интеллектуальной элиты и особенно от политиков, ученых обществоведов, экономистов сформировать и предложить новую концепцию развития мира.Складна сучасна політична, соціально-економічна, міжнаціональна, релігійна та ін. ситуація в суспільстві вимагає від інтелектуальної еліти і особливо від політиків, вчених суспільствознавців, економістів сформувати та запропонувати нову концепцію розвитку суспільства.Complicated modern political, socio-economic, international, religious and other situations in the world call on all the brainpower and especially policy-makers, scholars, social scientists, economists to elaborate and offer a new concept of the world development

Evaluating Generative Ad Hoc Information Retrieval

Recent advances in large language models have enabled the development of viable generative information retrieval systems. A generative retrieval system returns a grounded generated text in response to an information need instead of the traditional document ranking. Quantifying the utility of these types of responses is essential for evaluating generative retrieval systems. As the established evaluation methodology for ranking-based ad hoc retrieval may seem unsuitable for generative retrieval, new approaches for reliable, repeatable, and reproducible experimentation are required. In this paper, we survey the relevant information retrieval and natural language processing literature, identify search tasks and system architectures in generative retrieval, develop a corresponding user model, and study its operationalization. This theoretical analysis provides a foundation and new insights for the evaluation of generative ad hoc retrieval systems.Comment: 14 pages, 5 figures, 1 tabl

Overview of the 5th International Competition on Plagiarism Detection

Abstract This paper overviews 18 plagiarism detectors that have been evaluated within the fifth international competition on plagiarism detection at PAN 2013. We report on their performances for the two tasks source retrieval and text alignment of external plagiarism detection. Furthermore, we continue last year’s initiative to invite software submissions instead of run submissions, and, re-evaluate this year’s submissions on last year’s evaluation corpora and vice versa, thus demonstrating the benefits of software submissions in terms of reproducibility.Potthast, M.; Hagen, M.; Gollub, T.; Tippmann, M.; Kiesel, J.; Rosso, P.; Stamatatos, E.... (2013). Overview of the 5th International Competition on Plagiarism Detection. CLEF Conference on Multilingual and Multimodal Information Access Evaluation. 301-331. http://hdl.handle.net/10251/46635S30133

High correlation of temporal muscle thickness with lumbar skeletal muscle cross-sectional area in patients with brain metastases.

OBJECTIVES: This study aimed to assess the correlation of temporal muscle thickness (TMT), measured on routine cranial magnetic resonance (MR) images, with lumbar skeletal muscles obtained on computed tomography (CT) images in brain metastasis patients to establish a new parameter estimating skeletal muscle mass on brain MR images. METHODS: We retrospectively analyzed the cross-sectional area (CSA) of skeletal muscles at the level of the third lumbar vertebra on computed tomography scans and correlated these values with TMT on MR images of the brain in two independent cohorts of 93 lung cancer and 61 melanoma patients (overall: 154 patients) with brain metastases. RESULTS: Pearson correlation revealed a strong association between mean TMT and CSA in lung cancer and melanoma patients with brain metastases (0.733; p<0.001). The two study cohorts did not differ significantly in patient characteristics, including age (p = 0.661), weight (p = 0.787), and height (p = 0.123). However, TMT and CSA measures differed significantly between male and female patients in both lung cancer and melanoma patients with brain metastases (p<0.001). CONCLUSION: Our data indicate that TMT, measured on routine cranial MR images, is a useful surrogate parameter for the estimation of skeletal muscle mass in patients with brain metastases. Thus, TMT may be useful for prognostic assessment, treatment considerations, and stratification or a selection factor for clinical trials in patients with brain metastases. Further studies are needed to assess the association between TMT and clinical frailty parameters, and the usefulness of TMT in patients with primary brain tumors

Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma

Background Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several cancer types. Methods We performed immunohistochemistry for CD3, CD8, CD20, HLA-DR, phosphatase and tensin homolog (PTEN), PD-1, and PD-L1 and pyrosequencing for assessment of the O6-methylguanine-methyltransferase (MGMT) promoter methylation status in 135 glioblastoma specimens (117 initial resection, 18 first local recurrence). PD-L1 gene expression was analyzed in 446 cases from The Cancer Genome Atlas. Results Diffuse/fibrillary PD-L1 expression of variable extent, with or without interspersed epithelioid tumor cells with membranous PD-L1 expression, was observed in 103 of 117 (88.0%) newly diagnosed and 13 of 18 (72.2%) recurrent glioblastoma specimens. Sparse-to-moderate density of tumor-infiltrating lymphocytes (TILs) was found in 85 of 117 (72.6%) specimens (CD3+ 78/117, 66.7%; CD8+ 52/117, 44.4%; CD20+ 27/117, 23.1%; PD1+ 34/117, 29.1%). PD1+ TIL density correlated positively with CD3+ (P < .001), CD8+ (P < .001), CD20+ TIL density (P < .001), and PTEN expression (P = .035). Enrichment of specimens with low PD-L1 gene expression levels was observed in the proneural and G-CIMP glioblastoma subtypes and in specimens with high PD-L1 gene expression in the mesenchymal subtype (P = 5.966e-10). No significant differences in PD-L1 expression or TIL density between initial and recurrent glioblastoma specimens or correlation of PD-L1 expression or TIL density with patient age or outcome were evident. Conclusion TILs and PD-L1 expression are detectable in the majority of glioblastoma samples but are not related to outcome. Because the target is present, a clinical study with specific immune checkpoint inhibitors seems to be warranted in glioblastom

Evaluation of the Temporal Muscle Thickness as an Independent Prognostic Biomarker in Patients with Primary Central Nervous System Lymphoma.

In this study, we assessed the prognostic relevance of temporal muscle thickness (TMT), likely reflecting patient's frailty, in patients with primary central nervous system lymphoma (PCNSL). In 128 newly diagnosed PCNSL patients TMT was analyzed on cranial magnetic resonance images. Predefined sex-specific TMT cutoff values were used to categorize the patient cohort. Survival analyses, using a log-rank test as well as Cox models adjusted for further prognostic parameters, were performed. The risk of death was significantly increased for PCNSL patients with reduced muscle thickness (hazard ratio of 3.189, 95% CI: 2-097-4.848, p < 0.001). Importantly, the results confirmed that TMT could be used as an independent prognostic marker upon multivariate Cox modeling (hazard ratio of 2.504, 95% CI: 1.608-3.911, p < 0.001) adjusting for sex, age at time of diagnosis, deep brain involvement of the PCNSL lesions, Eastern Cooperative Oncology Group (ECOG) performance status, and methotrexate-based chemotherapy. A TMT value below the sex-related cutoff value at the time of diagnosis is an independent adverse marker in patients with PCNSL. Thus, our results suggest the systematic inclusion of TMT in further translational and clinical studies designed to help validate its role as a prognostic biomarker

Report on the future conversations workshop at CHIIR 2021

The Future Conversations workshop at CHIIR’21 looked to the future of search, recommen- dation, and information interaction to ask: where are the opportunities for conversational interactions? What do we need to do to get there? Furthermore, who stands to benefit?The workshop was hands-on and interactive. Rather than a series of technical talks, we solicited position statements on opportunities, problems, and solutions in conversational search in all modalities (written, spoken, or multimodal). This paper –co-authored by the organisers and participants of the workshop– summarises the submitted statements and the discussions we had during the two sessions of the workshop. Statements discussed during the workshop are available at https://bit.ly/FutureConversations2021Statements